SUBJECT

Title

Molecular Cell Biology

Type of instruction

lecture

Level

master

Part of degree program
Credits

4

Recommended in

Semester 1

Typically offered in

Autumn semester

Course description

Origin and universal features of the cells,
Structure and function of the nucleus,
DNA replication, repair and recombination,
Control of gene expression,
Intracellular compartmentalisation of the cell
Intracellular vesicular trafficingand protein sorting
From DNA to RNA, from RNA to protein
Co- and port-translational controls
The cytosceleton and molecular motors
Components of cell cycle control system
Intracellular control of cell cycle
Mechanics of cell division
Peroxisomes, gyloxisomes, hidrogenosomes
Energy conversion: the mitochondrion and the electrontransport chains
General principles of cell communication, signaling pathways
Cell junctions, cell adhesion and the extracellular matrix
Molecular and cellular basis of cancerogenesis
Mechanisms of programmed cell death, apoptosis, autophagocytosis
Regulation of cell death
Histology,: the lives and deaths of cells in tissues

Readings
  • Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K. and Walter, P.: Molecular Biology of the Cell
  • Taylor & Francis, 2014, ISBN 9780815344322
  • Darnell, J., Lodish, H. and Baltimore D.: Molecular Cell Biology, W. H. Freeman, 2012, ISBN 9781429234139