SUBJECT

Title

Infectional Immunology

Type of instruction

lecture

Level

master

Faculty

Faculty of Science

Part of degree program

Biology MSc

Credits

Recommended in

Semester 3

Typically offered in

Autumn semester

Course description

1. Introduction. Cellular and humoral elements of the immune system. Generation of immune response, elimination of antigens.

2. Innate and adaptive responses to various types of pathogens - general features.

3. Characterization of various T-cell subtypes (Tc, Th1, Th2, Treg cells) and description of their role in the development and regulation of response to pathogens.

4. Immune response against extracellular bacteria.

5. Immune response against multicellular parasites.

6. Immune response against intracellular bacteria.

7. Immune response against intracellular parasites.

8. Immune response against viruses - differences in the response to periodically activated and persisting viruses, role of memory cells.

9. Infection with influenza-virus, zoonosis, bird-flue.

10. Sexually transmitted pathogens (eg. HIV, Hepatitis, Herpes, Papilloma-virus), typical symptoms and possible treatments.

11. Infections caused by fungi and characteristics of immune response against the pathogens.

12. Escape mechanisms of pathogens. Modulation of the immune system by viruses.

13. Generation and maintanence of immunological memory.

14. Vaccination - various forms and mechanisms of generating immune defense.

Readings

Kenneth M. Murphy: Janeway's Immunobiology, 6th Ed., Garland Science, 2011