SUBJECT

Human Microbiology

lecture

master

Faculty of Science

Biology MSc

2

Semesters 1-4

Autumn/Spring semester

1. Ecological basis of human-microbe interactions. Symbiosis, mutualism, proto-cooperation.

2. Pathogenecity, virulence, virulence factors. The effect of age, gender and human genotype on the symbiosis.

3. Microbial communities of human skin. Organisation of the aerobe and anaerobe microbiota. Skin „microbiogeography”. Microbiology of wounds, acne, folliculitis, etc. Scalp and sole of the foot, body odour and microbes.

4. Microbiology of the oral cavity and teeth. Plaque formation, caries, periodontal diseases.

5. Microbiology of the gastrointestinal tract. Stomach bacterial communities and gastric ulcer.

6. Microbial dynamics of small and large intestines. The role of VFA in human nutrition. Microbes of the faeces.

7. Microbiology of the respiratory tract. Nose, pharynx, larynx, trachea, bronchi and alveoli. Sinusitis, otitis media.

8. The indigenous microbiota of the urinary tract and the reproductive system. Differences in the microbiology of male and female.

9. Sexually transmitted diseases.

10. Microbiology of the eye. Interactions among members of ocular microbiota. Contact lens wear.

11. Microbial colonisation of newborns, development of the microbial communities in the intestine and the skin.

12. Basics of personal hygiene. Role of microbes in maintaining human health.

13. The microbiologically healthy workplace and home environment. SBS. Microbiology of community places from schools to plazas.

14. Manipulation of the indigenous microbiota. Pro- and prebiotics. Special health care replacement therapies.

• Wilson, M. 2005. Microbial Inhabitants of Humans. Cambridge Univ. Press, Cambridge.