SUBJECT

Nuclear Methods with Applications in Biology

lecture

Master

Faculty of Science

Chemistry MSc

2

Semesters 1-4

Autumn/Spring semester

Review of the basics of nuclear chemistry, application of radiation for diagnostic purpose and for its radiation effect. Nuclear techniques in biology: isotope dilution, radioimmunoassay, radiotracer techniques in plant and animal physiology as well as in human application. Preparation and application of isotopically labelled compounds, PET-diagnostics, CT and other imaging techniques. Radiotherapy, nuclear medicine, biological consequences of radiation exposure. The basics of stable isotope labelling and applications in analytical chemistry; isotope effects.

Compulsory: 

• Attila Vértes, István Kiss: Nuclear Chemistry, Akadémiai Kiadó, Budapest, 1987

Suggested:

• Handbook of Nuclear Chemistry, ed. A. Vértes, S. Nagy, Z. Klencsár, Kluwer Academic Publishers, 2003 (relevant chapters) 

• Joseph Magill, Jean Galy: Radioactivity, Radionuclides, Radiation, Springer, Berlin, 2005

• G. Choppin, J.O. Liljenzin, J.Rydberg, Radiochemistry and Nuclear Chemistry, Butterworth-Heinemann, 2002