SUBJECT
Medical Genomics
lecture
master
2
Semesters 1-4
Autumn/Spring semester
1. Basic genomics; Human genome;
2. General characteristics of multifactorial diseases;
3. Methods for the investigation of the genetic ground of multifactorial diseases;
4. Molecular pathomechanism of allergic asthma; Genomic ground of allergic asthma;
5. Molecular pathomechanism and genomic ground of type 1 diabetes mellitus;
6. Molecular pathomechanism and genomic ground of type 2 diabetes mellitus;
7. Molecular pathomechanism and genomic ground of obesitas;
8. Locusos, genes, gene variations behind obesity;
9. Molecular pathomechanism and genomic ground of hypertension;
10. Molecular pathomechanism and genomic ground of atherosclerosis;
11. Genomic ground of Alzheimer disease, Parkinson disease; psychogenomics
12. Role of gene-environmental interaction in the multifactorial diseases;
13. Examples from the pharmacogenomic results of the multifactorial diseases.
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Strachan T, Read AP: Human Molecular Genetics 2; (also online through PubMed)
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PubMed, Garland Science, 2004